Imlook4d started as a viewer for 4-dimensional viewer for medical PET, CT, MRI images, but has for more than a decade evolved to include tools typically not available. The most important feature is the easy method to extend functionality by adding a single matlab script into a folder (resulting in it becoming an integrated menu in imlook4d).
Figure: imlook4d PET/MRI with applied temporal Hotelling filter
Easy method: Download from the imlook4d web site (https://sites.google.com/site/imlook4d)
The program is developed in Matlab and works on all platforms
Some features of imlook4d:
Full 4D Viewer.
VOI analysis, using brush tool (easier than polygons), and thresholded brushing.
PET pharmaco-kinetic modelling (9 models, both on ROIs and parametric images)
DICOM, Nifti, Analyze, ECAT (very fast compared to Matlabs routines), and reads binary, interfile
Handles time-information in DICOM-converted Niftis, and reads PMOD-Nifti format.
Export/Import to Matlab, gives full access to data in Matlab workspace
Drop-in SCRIPTS (written in Matlab) makes it easy to add matlab code to imlook4d menues
Some 70 useful scripts for Matrix and ROI processing
Integrated with SPM (align, co-register, fit to atlas, …)
Integrated with ImageJ (move data back and forth between imlook4d and ImageJ)
Interactive help, click on the GUI or menu, and a detailed help opens
Requirements: Windows, Linux or MacOS, and Matlab with no extra toolboxes. A few features are nicer with imaging toolbox